I got the following example from Ben Bradley about a completely different topic, but since it raises interesting issues about the afterlife I figured I'd steal it and ask some questions about it.
Suppose you had a terminal illness. You're given six months to live. There's a treatment that can save you, but it will lead to a total transformation of your personality and interests. For example, you might stop enjoying philosophy and the intellectual life and start enjoying bottle cap collecting. You would find complete fulfillment in bottle cap collecting and not miss the intellectual life, but the desires you currently have would no longer be fulfilled. Ben poses the case as a means to wondering whether it would be better to die in six months or to undergo the treatment and be transformed so drastically that your current desires and preferences would very likely go unfulfilled.
My question is this: what significance does this case have for the possibility or nature of an afterlife? More particularly, what should someone who is not a univeralist say about this sort of case? If I need to spell out the details of what I'm thinking to guide the discussion in the direction I've been thinking, I will, but I'd rather see what people want to say about it first.